Toxicol Lett 2005;155:411-20. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. Z Phytotherapie 2000;21:127-134. Company number 02758955 Registered VAT number 211727395. Three clinical studies have provided evidence that ointments containing comfrey root have helped reduce back pain. Squish and squeeze as many leaves into as you can into the container. Patients with hypersensitivity or allergic reactions to the plant should also avoid external use. The use of babosa (Aloe vera) in treating burns: a literature review. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Aust.Fam.Physician 2008;37(4):235-236. The most common over-the-counter medication that can be toxic to the liver is acetaminophen (Tylenol). CLICK HERE TO ENTER! You can purchase the Comfrey Ointment at Boots, Tesco, Sainsbury's or Holland & Barrett. For that reason, Ive also included my go-to comfrey cream recipe for achy joints and muscles! The recipe makes about 6 small jars. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. 2012;20(11):1209-16. doi:10.1016/j.joca.2012.07.019, Zago LR, Prado K, Benedito VL, Pereira MM. 12 drops juniper berry (Juniperus communis) essential oil When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. To make this recipe, first, you must prepare the comfrey root tincture. An ankle sprain can come out of nowhere and cause a lot of pain, limitations, and regret until it is healed. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. View abstract. Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. In a randomized multicenter study with 164 ankle sprain patients, swelling and pain were improved more successfully using a comfrey root extract compared to a diclofenac gel (Predel et al., 2005). This recipe is contraindicated for small children and those with certain medical conditions. A systematic review and quality assessment of case reports of adverse events for borage (Borago officinalis), coltsfoot (Tussilago farfara) and comfrey (Symphytum officinale). Sowa I, Paduch R, Strzemski M, et al. (2001). comfrey cream holland and barrett. A critical scoping review of external uses of comfrey (Symphytum spp.). Nyman) in children: A randomized double-blind study. Kuera, M., Barna, M., Horek, O., Kovrikov, J., & Kuera, A. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Br J Sports Med. Smith DB, Jacobson BH. If you choose to use comfrey, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Topically, comfrey root and leaf extracts have been traditionally used for bruises, sore muscles and joints, sprains, mild wounds, and gout (Natural Medicines, 2020). Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). Scientific studies have shown comfrey oil can help reduce the likelihood leg ulcers will become infected.7, Topical application of comfrey oil has been shown to support the lower and upper back more than methyl nicotinate, the main ingredient in many muscle creams.8. Cbd Oil In Holland And Barrett. Penetration of lycopsamine from a comfrey ointment through human epidermis. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Gyorik, S. and Stricker, H. Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy. Staiger, C. Comfrey root: from tradition to modern clinical trials. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. All rights reserved. Efficacy of a comfrey root (Symphyti offic. Wien Med Wochenschr. (Grube et al., 2007). The internal or extensive topical use of comfrey cannot be recommended because of numerous reports of liver damage. Using different formulations together increases the risk of an overdose. This leads to cirrhosis and eventually liver failure. Registered office: Samuel Ryder House, Barling Way, Nuneaton, Warwickshire CV10 7RH. Osteoarthritis.Cartilage. 2010;44(9):637-41. doi:10.1136/bjsm.2009.058677, Cameron M, Chrubasik S. Topical herbal therapies for treating osteoarthritis. randomized, placebo-controlled, double-blind, multi-clinical trial. 2020;142:104519. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. It's found in Europe, Asia, and North America. This is the tincture. Combination of comfrey root extract plus methyl nicotinate in patients with conditions of acute upper or low back pain: a multicentre randomised controlled trial. Registered VAT no. How do you use it and are there any side effects? Natural Standard. Many of those following the folk use of comfrey up to present-day think so. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Phytomedicine. 2010;73(2):97-100. In Western Europe, comfrey has been used topically for treating inflammatory disorders such as arthritis, gout, and thrombophlebitis, and internally for treating diarrhea. Acupuncture for Chronic Pain: Update of an Individual Patient Data Meta-Analysis. Bagheri Z, Azizi A, Oshvandi K, Mohammadi Y, Larki-Harchegani A. Liver injury from herbal and dietary supplements. View abstract. Registered in England: company no. Beth Thomas, PharmD, is a clinical pharmacist and founder of BMT Consulting Services, LLC. Comfrey root extracts have been used by herbalists and in folk traditions for centuries to soothe aches and pains. As a Licensed Massage Therapist, I have personally made this comfrey cream recipe multiple times and given jars to my clients. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. Supplements marketed for body-building (ex.. Limited trials have evaluated the effectiveness of alkaloid-free preparations for external use; however, these studies did not examine how much liver damage occurred in patients. Most comfrey oils keep for around 2 years after production. The Herbal Academy supports trusted organizations with the use of affiliate links. J Pharm.Belg. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Skin patch test before use, especially if you have sensitive skin, and never use on a deep wound. comfrey cream holland and barrettfeathered friend questions and answers. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Comfrey is considered likely unsafe to use during pregnancy. Like any new treatment, discontinue use if any irritation occurs. Credit Solution Experts Incorporated offers quality business credit building services, which includes an easy step-by-step system designed for helping clients build their business credit effortlessly. Further study is needed to confirm these results. Comfrey also is known as Russian comfrey, knitbone, radix consolidate, bruisewort, blackwort, and slippery root. After eight days, the group that used the cream had significantly less pain than those who had the placebo. Comfrey is not recommended for internal use because of the liver damage caused by its pyrrolizidine alkaloids. Potters Comfrey Oil | Holland & Barrett Shop our range of Potter's Herbals products at Holland & Barrett, including Potters Comfrey Oil. Latest: Senior Software Engineer - Front End Senior Software Engineer Senior Product Manager - Basket, Checkout and Payments UX Designer - Instore Tech. 2013;5(5):CD010538. Click to share on Facebook (Opens in new window), Click to share on Pinterest (Opens in new window), Click to share on Twitter (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Tumblr (Opens in new window), Click to share on Reddit (Opens in new window), Click to email a link to a friend (Opens in new window), Try A Cooling Herbal Compress for Hot Summer Days, Handmade Floral Paper: A Family-Friendly Project, Making Herbal Preparations 101 Mini Course, Emulsifiers and Preservatives in Botanical Skin Care Products. https://doi.org/10.1007/s10354-007-0474-y. Comfrey is an herb in the Boraginaceae family and has small purple flowers. We comply with the HONcode standard for trustworthy health information. Small glass jars with lids for sharing (optional). Discard after a year or according to labeling. Be sure to use comfrey root from a reputable source that has properly identified the species. Of course, more research is needed to validate efficacy and safety. Copyright Holland & Barrett Limited 2023. Allow the oil mixture to cool until it reaches room temperature, which could take 8-12 hours. Version: 5.01. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Herbal drugs and phytopharmaceuticals. July 6, 2001. Megan Nunn, PharmD, is a community pharmacist in Tennessee with over twelve years of experience in medication counseling and immunization. Verywell Health's content is for informational and educational purposes only. Copyright 1996-2023 Cerner Multum, Inc. CBD oils being bought in high street stores such as Boots and Holland & Barrett are weak, low quality and don't provide the actual therapeutic advantages. Select a condition to view a list of vitamins. View abstract. Phytomedicine, 11(6), 470-477. https://doi.org/10.1016/j.phymed.2004.02.001, Kucera, A., Barna, M., Holcova, S., Horacek, O., Hladikov, M., & Ottillinger, B. Label with the ingredients and date made. This is because only a small amount of the pyrrolizidine alkaloids are absorbed through the skin (Jedlinszki et al., 2017). 4-4-2009;139(13-14):210-211. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Researchers have investigated the effects of comfrey cream on several health conditions. Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. Herbal medicine for low back pain: A Cochrane review, Dietary Supplements: What You Need to Know, Sinusoidal obstruction syndrome (blockage of veins in the liver). Amendments to the poison list. This site uses cookies to improve your experience. This is done by soaking the root in at least 50% alcohol for a minimum of two weeks. The Food and Drug Administration (FDA) released an advisory in July 2001 recommending that comfrey products be removed from the market because of cases of hepatic veno-occlusive disease. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. 2013;27(6):811-7. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. 2005 - 2023 WebMD LLC. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study. Regul Toxicol Pharmacol. When buying commercial brands, seek those that have had the pyrrolizidine alkaloids removed, if possible. It's typically only used in small amounts for a very short period. Resuscitation 2008;76(3):323-324. Stickel F, Seitz HK. Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. Since these toxic substances can be absorbed through the skin, there's concern about the safety of comfrey cream applied topically. Comfrey contains chemicals that can cause liver damage, lung problems, or cancer. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. 6 Healing Benefits of Comfrey. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. It is called knitbone or boneset, referring to the bone-like growth of its roots. Some drugs increase how quickly the liver changes and breaks down comfrey. View abstract. Readers must do their own research concerning the safety and usage of any herbs or supplements. It may contain small amounts of toxic pyrrolizidine alkaloids. The participants were assigned three weeks of treatment with two grams of either comfrey ointment or a placebo three times a day. Laslett, L. L., Quinn, S. J., Darian-Smith, E., Kwok, M., Fedorova, T., Korner, H., Steels, E., March, L., and Jones, G. Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. Centurian, South Africa: Medpharm Scientific Publishers. View abstract. A few studies show that comfrey cream may be helpful in the treatment of ankle sprains. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. Comfrey has long been used in folk traditions for bruising and abrasions. Apply a small amount (not to exceed a teaspoon) topically 2-3x/day for up to 2 weeks. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Many of those following the folk use of comfrey up to present-day think so. June 3, 2022 Posted by: Category: Uncategorized; No Comments . In some cases, ointments with comfrey have caused redness, itching, and a rash (Smith, 2011). 2004;154(21-22):498-507. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements. All rights reserved. Koll, R., Buhr, M., Dieter, R., Petrowicz, O., Gianetti, B., and Wagener, S. Wirksamkeit und Vertraglichkeit von Beinwellextrakt (Extr. Researchers have found it does seem to reduce pain in some conditions, including back pain, osteoarthritis, and ankle sprains. Effects of Symphytum ointment on muscular symptoms and functional locomotor disturbances. Swiss.Med.Wkly. Please read the Topical Use Safety section of this article (above) before using. Close LOGIN FOR DONATION. Grube, B., Grunwald, J., Krug, L., and Staiger, C. Efficacy of a comfrey root (Symphyti offic. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This information may not fit your specific health circumstances. Discontinue use if a rash develops. Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. cup organic, unrefined cocoa butter Heat oil in double boiler gently then add beeswax until it melts. View abstract. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. Avoid comfrey with certain medical conditions, such as liver disease. Generic name: comfrey [COM-free] Studies in humans are very limited. These include allantoin, rosmarinic acid, and others. For External Use only Do not use if you are sensitive to any of the ingredients. Complementary Health Approaches for Chronic Pain: What the Science Says. Knee pain and stiffness can be a stubborn concern that keeps many from doing activities they enjoy. The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. Fortschr Med Orig 2002;120:1-9. 2016 Jan;41(2):116-33. doi:10.1097/01.brs.0000249525.70011.fe. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. This site uses cookies to improve your experience. Symphyti) bei Sprunggelenks-distorsionen. 211727395. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. View abstract. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Finally, well warn of any side effects associated with comfrey oil. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. We go to great efforts to ensure that the information on this page is accurate at the time that the page was last edited. With extract of Comfrey. Understand comfreys contraindications before using it. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: Results of a double-blind, randomised, bicenter, placebo-controlled trial. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. However, not a rate considered harmful for those with healthy livers.10,11, Masters Degree in Toxicology and BSc Hons in Medical Biochemistry. Do not use more of this product than is recommended on the label. Toe was infected and painful. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? Set aside cup for the cream recipe and store the rest in a glass jar. Retrieved from https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295, Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). View abstract. Copyright Holland & Barrett Retail Limited, 2022. The following applications have been used in research: Using large amounts of comfrey cream or using it for extended periods of time increases the risk of side effects like liver toxicity. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Preclinical studies suggest that oral comfrey has antiproliferative effects , and a topical formulation showed wound healing properties . cup organic safflower oil Contact your doctor or pharmacist if you have any questions before use. Cap, then label the jars with the date made and ingredients. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. ). Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Experts suggest not using comfrey cream for longer than ten days in a row. The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). This is not a complete list of side effects and others may occur. Follow all directions on the product label and package. Study results revealed that pain intensity during active movement decreased an average of 95.2% in the group given comfrey ointment. Mix for about 10 minutes, until nice and whipped. The way that they work is by blocking small blood vessels in the liver. 2012;(1):41-42. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. Ulbricht, C. (2010). The Pharmaceutical Journal, PJ, December 2007. Transfer the cooled oil and butter mixture to a standing electric mixer or blender. Ther Drug Monit 2001;23:698-708. We cover all you need to know in this article. Registered in England: company no. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The Comfrey Controversy: Can and Should One Use Comfrey Internally? A symptomatic treatment of minor sprains and bruises. In a randomized, controlled, double-blind study with 203 patients, applications of a 10% comfrey cream were well tolerated, reduced swelling and pain, and improved mobility (Kucera et al., 2004). Add cup of the comfrey tincture and all essential oils to the cooled oil/butter mixture. International Journal of Pediatrics and Adolescent Medicine, (4), 135-141. https://doi.org/10.1016/j.ijpam.2018.11.002. No comments. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy. Comfrey can kill. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. An Evidence-Based Reference. Add comfy to Vaseline . Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. One study followed 142 patients with ankle sprains. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Arzneimittelforschung. When considering the use of herbal supplements, seek the advice of your doctor. While larger and more studies are needed to fully determine safety and effectiveness, short term topical application of comfrey may give you peace of mind, relief, and support while you rest and heal, following any additional advice from your physician. After the consistency begins to thicken, turn the mixer up a little bit. Bleakley, C. M., McDonough, S. M., and MacAuley, D. C. Some conservative strategies are effective when added to controlled mobilisation with external support after acute ankle sprain: a systematic review. These side effects may be common or severe. 2010;13(7-8):509-526. doi:10.1080/10937404.2010.509013, Staiger C. Comfrey: A clinical overview. hollandandbarrett.ie is a trading name of Holland & Barrett Retail Limited. Eucalyptus oil is used externally to stimulate blood flow. Food and Drug Administration. Adv Ther 2005;22(6):681-692. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Comfrey is often sold as an herbal supplement. Comfrey is traditionally used for the symptomatic treatment of minor sprains and bruises and is also known for its healing properties. Liver injury from herbal and dietary supplements. British journal of sports medicine, 44(9), 637-641. https://doi.org/10.1136/bjsm.2009.058677, Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). Wien.Med Wochenschr. Call your doctor if the condition you are treating with comfrey does not improve, or if it gets worse while using this product. Brassica Campest is Seed Oil (Rapeseed Oil), Symphytum Officinale Herb (Comfrey Herb), BHA, Eucalyptus Globulus Leaf Oil (Eucalyptus Oil). Some medications can also harm the liver. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products. . Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Yield: Approximately 5 cups of whipped lotion. Comfrey cream may help treat knee osteoarthritis, according to a Cochrane review of topical herbal therapies. Comfrey should not be used in place of medication prescribed for you by your doctor.

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